Bolus dispersion issues related to the quantification of perfusion MRI data
نویسندگان
چکیده
منابع مشابه
Quantification Issues in Bolus-Tracking Perfusion MRI
Bolus-tracking perfusion MRI is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly in the antecubital vein in the patients arm by means of an MR-compatible power injector. This bolus of contrast agent is pushed in the direction of the heart by means of a saline flush. Continuous dy...
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Introduction Quantification of myocardial blood flow by means of dynamic T1-weigthed MRI requires the knowledge of the arterial input function (AIF). In first pass myocardial perfusion imaging the AIF is usually estimated from the left ventricle (LV) [1-3]. Dispersion of the contrast agent bolus may occur between the LV and the tissue of interest, e.g. as a result of the vascular flow profile, ...
متن کاملCardiac magnetic resonance dual bolus myocardial perfusion quantification superior to the single bolus analysis method
Methods In this substudy of the NOMI-trial (ClinicalTrials.gov identifier: NCT01398384), CMR rest and adenosine stress perfusion were analyzed in 119 patients at 4 months after acute myocardial infarction with TIMI 2-3 flow after primary PCI. A balanced turbo gradient echo sequence with non-shared prepulse was used in 1.5 tesla MR scanner (Achieva, Philips Medical Systems). MBF was quantified u...
متن کاملDynamic susceptibility MRI with a pre-bolus administration design for improved absolute quantification of perfusion
Purpose Reproducible absolute quantification of cerebral blood volume (CBV) and cerebral blood flow (CBF) by dynamic susceptibility contrast MRI (DSC-MRI) is difficult to achieve, for example, due to partial-volume effects (PVEs). Rescaling of the arterial input function (AIF) using a corrected venous output function (VOF) in DSC-MRI has been shown to improve the correlation between CBF estimat...
متن کاملMyocardial perfusion SPECT: Perfusion quantification
Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2005
ISSN: 1053-1807,1522-2586
DOI: 10.1002/jmri.20454